Mauro,
My suggestions are to leave the RGB settings on the camera alone. The default settings provided by the driver are fine. I shoot all of my LIGHTs, FLATs, BIAS, DARKs etc at 1x1 binning. Once you have a stacked result you can determine if binning is needed. If you bin your flats at 2x2 then everything else has to be binned 2x2. Don't be thinking about saving disk space. If you are running out of disk space then consider buying an external USB drive and pull all the files you don't immediately need onto it.
Peter